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Thymalfasin for Injection

【 Brand 】 Hanjia ®

[Drug Name] Thymus injection method new

[Indications] Chronic hepatitis B - This product is used to treat those patients with chronic hepatitis B who are 18 years old or older, whose liver disease is compensatory, and have hepatitis B virus replication (positive serum HBV-DNA). The research conducted in those patients whose serum hepatitis B surface antigen (HBSAg) is positive for at least 6 months, and whose serum transaminase (ALT) is elevated shows that the treatment of this product can produce viral remission (loss of serum HBV-DNA) and normalization of transaminase levels. In some responsive patients, this product treatment can remove serum surface antigens. Clinical trials suggest that when this product is used in combination with alpha interferon, it may increase the response rate compared to using this product alone or interferon alone. As a vaccine booster for patients with immune impairment - those whose immune system function is inhibited, including those who receive chronic hemodialysis and elderly diseases, this product can enhance the immune response of patients to viral vaccines, such as influenza vaccine or hepatitis B vaccine. A study on hemodialysis patients showed that after receiving the influenza vaccine, 65% of patients who used this product as an adjuvant produced anti influenza virus antibodies with a titer level increased by more than 4 times, while only 24% of patients in the placebo group showed this response.

    Chemical Composition: 
    Thymalfasin is the synthetic equivalent of thymosin alpha 1, carefully formulated to ensure biological activity and stability. It is engineered to match the endogenous peptide’s structure, ensuring it effectively mimics the natural process of immune regulation.
    Mechanism of Action: 
    Thymalfasin works by stimulating the differentiation and maturation of T lymphocytes, essential cells in the adaptive immune system. It also influences the regulation of cytokines, which are critical in the immune response, enhancing the body’s defense mechanisms against pathogens and malignancies. The drug acts to restore immune system balance, promoting an effective response to infections and facilitating the immune surveillance against cancer cells.
    Indications and Usage: 
    This medication is indicated for use in treating chronic viral infections such as hepatitis B and C, where it helps improve the immune response to the virus. It is also used in oncology as an adjunct therapy to enhance the efficacy of cancer treatments. Additionally, Thymalfasin is beneficial in immune therapy for diseases where immune modulation is crucial.
    Administration and Dosage: 
    Thymalfasin is administered through subcutaneous or intramuscular injection. The dosage regimen varies depending on the condition being treated, with adjustments made based on the patient's response to therapy and specific clinical needs. Treatment duration and dosage are tailored to optimize therapeutic outcomes while minimizing side effects.
    Efficacy and Outcomes: 
    Clinical trials and studies have demonstrated the effectiveness of Thymalfasin in improving the immune response in patients with chronic hepatitis B and C, leading to better disease management and outcomes. In cancer therapy, it has shown promise in enhancing the body’s ability to combat tumor growth. The use of Thymalfasin in vaccine adjuvant therapy has also been explored, showing potential in improving vaccine efficacy.
    Side Effects: 
    The treatment is generally well-tolerated by patients, with reported side effects including mild injection site reactions, fatigue, and occasional flu-like symptoms. Serious adverse effects are rare, making Thymalfasin a safe option for immune system modulation.
    Contraindications and Precautions: 
    While Thymalfasin is beneficial for a wide range of patients, it should be used with caution in individuals with autoimmune diseases due to the potential for exacerbating symptoms. Healthcare providers should evaluate the risks and benefits for patients with a history of autoimmune conditions before initiating treatment.

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